Because I am getting old, I have some diseases like hypertension, chronic eye pressure disease, COPD/emphysema, some polyneuropathic itching when I go to bed (thanks to the extensive drinking in past decades), restless legs, pains in joints and tendons, but also such a disorder as hypernychthemeral syndrome. "The disorder is an invisible disability that can be 'extremely debilitating in that it is incompatible with most social and professional obligations'". Luckily it started only when I was about 50.

Alcoholism, but I have controlled it quite well in the last few years, especially in the last two years.

And a definite tendency to melancholy. That may be the worst!